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| Strain
Number: |
01X68 |
| Common
Strain Name: |
CAG-LSL-EGFRvIII |
| Strain
Nomenclature: |
STOCK Col1a1tm2(CAG-EGFR*)Char |
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| Release
Category (Required for MTA form):
B3
,
D
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| Animal Health Report in PDF Format |
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| Strain
Description: |
None until presented to tissue specific Cre recombinase. |
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| Mutation
Information |
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Mutation
Type: |
Targeted |
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Gene
Name: |
5'-mutant epidermal growth factor receptor
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Gene
Symbol: |
EGFRvIII
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Transgene
Name: |
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Transgene
Symbol: |
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Promoter
Name: |
CAGGS, chicken and viral |
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Promoter
Symbol: |
CAGGS |
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Current
Genetic Background: |
STOCK |
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Approx.
Generation: |
4 |
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Organ
Site : |
Any |
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Husbandry: |
Breeder pairs are supplied as a heterozygote (male or female) x wildtype FVB mate (male or female). Average litter size is 7. |
| Genotyping Information: |
Protocol 1: Allele: Col1a1
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| Donating
Investigator: |
Dr. Alain Charest |
| Key
Reference: |
Zhu et al., Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2712-6. PMID: 19196966 [PubMed - indexed for MEDLINE]PMCID: PMC2650331
[PubMED
Abstract]
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| Sponsoring Institute: |
National Institutes of Health U54 CA119349, U01 CA141556 |
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